Design of ACM life cycle is defined with respect to traffic load acting on the pavement and road class for a period of about 20 years.In practice, reconstruction is usually pending until the end of the life cycle after which the reconstruction takes place and the original materials are replaced by new materials.Life cycle of the pavement constructi
Hair is a unique biological matrix that adsorbs short-term exposures (e.g., environmental contaminants and personal care products) on its surface and also embeds endogenous metabolites and long-term exposures in its matrix.In this work, we developed an untargeted metabolomics workflow to profile both temporal exposure chemicals and endogenous metab
Chronic Bottle Bag venous insufficiency (CVI) is a leading vascular disease whose clinical manifestations include varicose veins, edemas, venous ulcers, and venous hypertension, among others.Therapies targeting this medical issue are scarce, and so far, no single venous valve prosthesis is clinically available.Herein, we have designed a bi-leaflet